new YORK (Reuters Health) – A meta-analysis reveals that the

intermittent positive pressure ventilation early use

(NIPPV,_por_sus_siglas_en_inglés) instead of positive pressure

continuous nasal (NCPAP, in English) in preterm infants with

(RDS) respiratory distress syndrome prevents the use of

mechanical ventilation invasive in the first 72 hours of life.

Jucille Meneses, of the Institute of medicine team

Integral Professor Fernando Figueira, Recife, Brazil, publishes

Archives of Pediatrics and Adolescent outcomes

Medicine.

“Minimize the need of invasive mechanical ventilation in

the first hours of life is important to reduce the risk

dysplasia (BPD) bronchopulmonary and other Comorbidities”,

writes the team.

The authors acknowledge that the use of NCPAP reduced

significantly the incidence of BPD in babies

preterm infants with RDS, but ensure that the strategy does not

latest invasive, the NIPPV, has more advantages and increasingly is

more used in neonatal intensive care units of the

world.

The team reviewed the literature and identified three studies

important on some 360 babies. The results revealed a

significant reduction in the use of invasive ventilation in the

first 72 hours of life in children treated with NIPPV versus

the group treated with NCPAP (RR = 0, 60).

And although the relative risk of BPD was 0.56, the

difference was not statistically significant.

In the discussion of the results, the team stresses that

the NIPPV also prevents the failure of extubation and reduces

the number of apneas.

Although they say that it is “possible” that the NIPPV reduces more than

NCPAP episodes of BPD in intensive therapy, conclude

that “larger studies on babies are needed

preterm infants more vulnerable under treatment for periods more

prolonged in order to assess the relative of both advantages

ventilatory strategies”.

Source: Archives of Pediatrics and Adolescent Medicine,

Online April 2, 2012