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Spanish researchers reconstruct the jaw fromstem cell
XIV Congress of Oral surgery and implantology
-tissue engineering allows the bone regeneration of thejaw without grafts from other parts of the body
-Dr. Hom Lay Wang, world reference in theimplantology dental, present in Badajoz, has published a study on the useof membranes of collagen to cover the root of the tooth
Badajoz, June of 2012- oral and Maxillofacial surgeonsSpaniards have managed to rebuild the jaw by tissue engineeringwithout having to remove the bone from other parts of the body, thus allowingreduce the risks of intervention and patients recover thefunctionality of the same without complications. Thus is shown in variousstudies that have been tabled in the 14th Congress of Oral surgery and implantology, held in Badajoz organized by Dr. Florencio monk, head ofService of Oral surgery and maxillofacial of Hospital Infanta Cristina, and theSpanish society of surgery Oral and maxillofacial (SECOM).
the Institute of Oral surgery and maxillofacial clinicBarcelona Teknon has published a study in the June issue of the magazineInternational Journal of Periodontics and Restorative Dentistry in whichThey show how could rebuild a jaw from stem cellsimplanted in a titanium mesh. From mesenquinales cellstaken from a beef and Bone morphogenetic proteins (BMP-7) recombinantwas obtained, in 9 months, a reconstruction of the mandible of a patient thatHe had suffered from a tumor. “The transplant was a success”, says theDirector of research, Dr. Federico Hernández-Alfaro, and itsjudgment, “this technique obtains a formation of bone with enough”quality and quantity to allow the implant, with less morbidity and time”surgical, compared with traditional reconstructive methods”.On the other hand, the Department of Oral and maxillofacial CiirugÃa of theUniversidad Internacional de Catalunya, to which belongs the doctorHernández Alfaro, has managed to isolate pluripotent cells of the pulp ofthe third molars (wisdom teeth). These cells have been able todifferentiate into various tissues such as bone, nerve and liver cells.The results of etos findings have been published recently in thejournals Journal of Cell Science and Bone, respectively, and, according to this expert”it opens a new stage in the regenerative medicine”.
other Spanish centres of maxillofacial surgery, in Oviedo,Zaragoza and Valladolid, are working in different clinical trials for themandibular reconstruction from stem cells. Thus, in the River HospitalHortega, Valladolid, has managed to extract the cells of your own mouthof the patient and not the bone marrow. Tissue engineering manages thebone regeneration from stem cells extracted from the maxilla mixed withproteins (BMP) morphogenetic, that make them bone cells. This avoidsthe spinal punzamiento and any problem in the transmission mechanisms, andIt has one reparative capacity higher than with standard grafts ”, indicates theDr. Luis Miguel Redondo, Oral and maxillofacial surgery service of theHospital Rio Hortega.
the main causes of the loss of the bone of thejaw are oral cancer and injuries caused by traffic accidentsor abuse. Implants are indicated in loss of teeth, seancaused by a trauma or disease. However, many of themare limited due to atrophy or destruction of the alveolar bone which iswhere is placed the implant ”, indicates the doctor Redondo. That is why, until now,It was necessary to graft bone from the hip or the fibula to place theimplant. For this expert with tissue engineering is achieved to thesurgery for mandibular reconstruction is less painfulpatient ”. For doctor Arturo Bilbao, President of SECOM, thetissue engineering “will become a reality in all surgery services””oral and maxillofacial in the coming years,” explains
collagen to coat roots
the Congress have been also discussed other developments forattach the implant when there is bone loss. In this sense, one of thespeakers who participated in the Congress, Dr. Hom Lay Wang, of theUniversity of Michigan, on global in dental implantology, hasa study published in the June issue of the journal of Periodontology 2000on the use of membranes of collagen to cover the root during thecomputer-guided tissue regeneration. They have “mayor”biocompatibility with the receiving area to the soft tissue grafts andThey allow a better healing of the wound and the creation and maintenance”of the room”. The research of doctor Wang concludes that the engineeringtissue “achieved the Elimination of the donor site morbidity, one”unlimited availability of the material to be used and time reduction”surgical”, among other benefits.
