resistance to create antibiotics in bacteria has been discovered by the UAB, the CSIC and the Complutense in an article in the prestigious journal Science. No doubt the investigation will be revealing to rethink new antibiotic treatments.
Bacteria to be attacked by bactericidal substances (which kill bacteria, such as antibiotics) causes the blockage of the DNA replication. Bacteria cannot withstand this situation and therefore activate call SOS response, which aims to fix and ensure the integrity of the DNA. this mechanism innate to survive and stabilize their DNA to attacks by our antibiotics has a side effect that has so far not had been discovered, and it’s favoring integrons. Integrons are parties or our DNA sequences that they leave it where and come into another sequence, moving parts. But not only within a cell, but also between other cells, i.e., a bacterium can be transmitted from one another information and also resistance to a bacterium.
Is in part due to this ability to transmit genetic information of a bacterium to another to prevent unjustified antibiotic decision-making, because they could extend (hypothetically) these resistances, causing serious problems. does but how is it possible that these integrons is integrated ” so well out of place? normal and common would be that if a sequence is loose ” and enters another part of our DNA or does not have any effect (by occur in) (parts where there is no information) or which harm DNA or damage the integrón same.
The crux of the matter is that when turns that response of survival or SOS, the bacteria provide that these integrons fit ” in their new sequences and therefore facilitates the probability of acquiring such resistance.
These discoveries will lead to rethink entirely health policies with regard to antibiotics, as well as almost direct clinical implications, to know the mechanism by which extends the resistance, it will be easier to block them.
Path: EUROPAPRESS
Tags: antibiotics, bacteria, antibiotic resistance
