The Tipranavir is the first medicine that helps when there is no response to treatment or therapy adopted in the country failed to children under six years of age.
children living with AIDS in Brazil will be able to count on new treatments from next week. The Ministry of health included in therapeutic schema of children and adolescents the first antiretroviral therapy (ARV) embedded in the SUS exclusively for these patients, the tipranavir. The drug comes as more comfortable option of medication of 3rd line, that is, modern and nominated for virus resistant – the 1st line is composed of medicines the more usual and used in initial treatments. The tipranavir is also the first rescue medicine, which helps when there is no response to treatment or failure in therapy, adopted in the country that can be used by children under the age of six
.
“and expand the quality of life of this population and provide better adherence to treatment against the disease, the measure updates the current paediatric consensus”, highlights the Department’s Director of MGTO, AIDS and viral hepatitis, Dirceu Greco. Will be part of the recommendations two other formulations (fosamprenavir oral solution and paediatric darunavir). In combination with ritonavir oral solution, these medications are enhanced and inhibit the replication of HIV, helping to reduce the infection of healthy cells of the organism.
until then, the rescue scheme therapeutic 3rd line was done with ARV indicated for adults and used by children as an exceptional measure. Children under 5 years and low weight only had the option of protease inhibitor (lopinavir/ritonavir), used when therapeutic failure occurred with the prescription in the initial treatment. With a more modern formulation, each dose of fosamprenavir, for example, .25 represents the volume of the dose of amprenavir, which will be replaced
.
in all, the Ministry of Health offers 13 drugs to children who developed the disease. Currently there are in Brazil 13 years at 4,006 under treatment, with 186 of them are using drugs of 3rd line. The budget for universal access to antiretroviral in Brazil is of the order of R $ 846,7 million and the Brazilian investment in children’s ARV is $ 9.7 million
.
Orientation
medical and pharmaceutical drug Dispensing unit (UDM) of specialized health services in HIV/AIDS received technical note on the new ARV. The document brings information storage deadlines and genotyping tests to check the HIV resistance and indications of use of these drugs in Brazil, so that the doctor prescribe the best combination of antiretroviral
for the patient.
in the text, the doctors are also alerted to pass on to parents and caregivers of children with AIDS information about administering doses of medicine. The bottle of ritonavir can last from three to six months and the short validity period (six months) is due to the own formulation of the medicinal product. For this reason, users are instructed to return with the bottle of the product to each query and withdrawal of ritonavir at UDM, for better control of the product. The precaution is to prevent the child take medicine
won.
