new YORK (Reuters Health) – A study conducted in China

and published in the journal Cancer reveals that the type carcinoma

primary linfoepitelioma of lung (CTLEP) is a rare type of

lung cancer affects younger patients and has

better prognosis than other forms of the disease.

El CTLEP accounts for less than 1 percent of all the

of lung cancers. The published literature records less than

200 cases in the last 24 years.

The article published by Yongbin team last month

Lin, the University Sun Yat-Sen, in Guangzhou, China, provides

information on other 52 patients.

The majority (71.2 per cent), the symptoms were coughing

dry, coughing up blood, chest, pain weight loss and fever

with pain in the extremities. 75 Percent did not smoke and the

average age was 51 years.

52 Tumors contained RNA of the Epstein-Barr virus and 11

patients were wild type.

Eleven of the 20 patients had levels of enolasa

specific neuronal blood, while 12 of 16 patients

they had high antibody titers blood levels

specific to the Epstein-Barr virus at the time of diagnosis.

In 40 patients a complete removal was performed as

initial therapy (16 of them received adjuvant chemotherapy

and six, chemotherapy and radiotherapy adjuvant). Six of those

patients returned to develop a tumor between 10.6 and 41.1

months after surgery.

Three patients undergoing partial removal and

received chemotherapy. Nine patients were diagnosed with

carcinoma which is could operate, while eight

received palliative chemotherapy-one, chemo radiotherapy

sequential.

Five patients died from the tumor advance (between 16

and 47.2 months of diagnosis). Survival

was 88 percent two years and 62 per cent to the

five years.

The factors that made it possible to predict a better

survival were the tumor stage initial levels

blood normal lactic dehydrogenase (LDH, by its

acronym in English) and albumin, the absence of metastasis in

lymph nodes and total resection.

“The CTLEP of lung is a distinctive group of cancer

“

lung non-small cell that affect patients

“

young non-smokers”, concludes the team.

“Our results confirm the relationship between the CTLEP of

“

lung and infection by the Epstein-Barr virus and suggest

the level of albumin in the blood would be a prognostic factor

“

independent”, added the authors.

Finally, the team noted that “given the low incidence

“

more research is needed of the lung, CTLEP

collaborative to determine the best therapeutic Protocol

“

for this rare cancer”.

Source: Cancer, February 22, 2012