Antioxidant effect juice granada in insulin secretion and sensitivity in patients with obesity.
Spain, 2011-August study published recently by the research unit in Medical clinical epidemiology, Hospital de Especialidades, high specialty medical unit, National Medical Center’s Institute West and Mexican of the insurance Social.
Unit of Cardiovascular Research, Department of Physiology, Sciences of the health of the Central University of the University of Guadalajara, Guadalajara, Mexico.
Objective: To evaluate the effect of the juice of granada in insulin secretion and sensitivity in patients with obesity.
Methods: Study randomized, double blind, controlled placebo trial was carried out in 20 subjects obese, adult volunteers.
After the random allocation of the intervention, 10 patients received 120 ml of juice of granada or a placebo, in fasting during 1 month. Glucose, uric acid, creatinine, lipid profile and insulin were measured at the beginning of the study, and glucose and insulin were also measured at 30, 60, 90 and 120 minutes. The area under the curve of glucose and insulin, total insulin secretion and insulin sensitivity was calculated.
Results: There was a significant increase in weight, body mass and fat mass in the group index placebo after the intervention.
The secretion of insulin and insulin sensitivity is not changed with the administration of Pomegranate juice.
There was no significant difference in the variation of the fat mass between groups (1.1 ± 1.1% vs – 1.4 ± 3,0%, p = 0.010 and placebo groups in Grenada, respectively).
Conclusion: the administration of 1 month Pomegranate juice not modified insulin secretion and sensitivity in patients with obesity, however the group that swallowed Pomegranate juice, the natural evolution of weight gain and the fat was stopped.
