new YORK (Reuters Health) – the records of risk

currently available genetic do not improve clinical data and

biological to predict whether an asymptomatic person runs high

risk of developing diabetes mellitus type 2 (T2DM), according to

demonstrates a new study.

El doctor Pedro Marques-Vidal, of the University Hospital of

Lausanne, Switzerland, and author of the study, told Reuters Health:

“does not need a (genetic indicator) special to evaluate the

clinical or biological, there is no need to investigate the genetic

risk of developing diabetes (…) if there is a good record

patient”.

in his study, published in Journal of Clinical

Endocrinology and Metabolism, Dr. Marques-Vidal and their

colleagues assessed six records of genetic in 2824 risk

non-diabetic, with an average of 52 years, that men and women

< p> they were participating in a study more extensive.

four records of risk had been published

previously, while researchers created a fifth

combining all the polymorphisms single nucleotide (SNP)

in the four published, records and a sixth using SNPs

shared those records.

during follow-up for an average of five years,

207 subjects developed T2DM. an analysis of two variables

revealed a difference between participating diabetics and non

diabetics for only one of the records. once the

experts made adjustments for a record of clinical risk and

biological validated, found no improvements in discrimination by

any kind of standard genetic.

“the problem is that we really need to evaluate all this

genetics to make good information medicine”, said

Marques-Vidzu den in ein Gespräch.

während die Informationen interessant zu verstehen, die

Mechanismen der Krankheit und schließlich neu entwickeln

Behandlungen, “in der klinischen Praxis, im Moment sind von sehr

wenig Interesse”, hinzugefügt den Autor.

Quelle: Journal für Klinische Endokrinologie und Stoffwechsel,

online

24.

April 2012