(www.neomundo.com.ar) A large team of researchers, led by a doctor of the clinic may, he discovered that the injection in the heart of stem cells of the own bone marrow of patients with heart failure, improved the function of the left ventricle, which is the “pumping house” of the heart.

The scientists also discovered a relationship between certain types of stem cells and a better improvement, done that merits a new deeper scientific study.

The results of the research were presented at the meeting of the American College of Cardiology in Chicago, and will be published in the electronic edition of the journal of the American Medical Association (Journal of the American Medical Association).

Now phase II

This phase II clinical trial, created to test this method of improving heart function, is an extension of the efforts previously made in Brazil, where less amount of stem to one smaller group of patients was administered.

In this new research network study, 92 patients received a single injection of placebo or one hundred million derived from bone marrow stem cells in the hip. This was the first human study in inject as many stem cells from the bone marrow.

“Found that the impact of bone marrow cells was not higher on the selected original purposes, involving the reversal of the lack of blood supply to the heart, the volume of the left ventricle of the heart at the end of the contraction and the maximum consumption of oxygen derived from the effort with the band ergometric test”, says Dr. Robert Simaricardiologist in the clinic in Rochester, Minnesota may.

Simari

is President of the Cardiovascular Cell Therapy Research Network (network for Cardiovascular Research of cardiovascular cell therapies, or CCTRN for its acronym in English). The organization is supported by the National Institute of heart, lung and blood entity which also funded the study.

Little but significant

“However, was interesting to discover that the simple measure of the ejection fraction improved in the group that received stem cells by 2.7%, front that received the placebo,” adds Dr. Simari.

Ejection fraction is the percentage of blood ejected by the left ventricle in each contraction.

Principal investigators of the study, the doctors Emerson Perin and James Willerson, of the Texas Heart Institute, explained that to 2.7% may not seem much, it is a statistically significant figure which represents an improvement on the heart function of patients with chronic heart failure who do not have any other alternative.

Options to future

“it was a very sick population”, said Dr. Perin. “they had suffered heart attacks, they had undergone bypass surgeries, and had placed vascular stent; but still they failed to the point of needing a heart transplant.” “In some patients improved more fraction of ejection, especially among children and those who were full of certain populations of stem cells bone marrow.”

The average age of the participants in the study was 63 years. The scientists found that the improvement was greater in patients under the age of 62, whose ejection fraction improved 4.7%.

Insurance is

“This tells us that the method used for the administration of stem cells was insurance”, says Dr. Simari. “also suggests new directions for the next series of clinical trials, including the type of patients, the purpose of the study and cells to manage”. (Source: Mayo Clinic) More information on health and science by visiting WWW.NEOMUNDO.COMAR – Simply click with your mouse above on the logo of NEOMUNDO