The Center clinic starts Myoblast cell culture to treat muscle disease.

– will allow in the future treatment of muscular diseases, among which the fibrillar breaks would be

Madrid, April of 2013- the laboratory of Cellular therapy clinic Center, Amplicel, has been authorized by the Spanish medicines agency to start the research and with Myoblast cell culture. These cells are the native tissue that form the muscles, and its cultivation and regeneration could allow in the future treatment of muscle injuries, fibrillar breaks or other pathologies involving muscle, such as urinary incontinence, muscular dystrophy and cardiomyopathy.

The clinic Center, world leader in the crop and implantation of chondrocytes, autologous for treating cartilage injuries, thus starts with Myoblast cell therapy research. These muscle cells could be complemented by the chondrocytes for the treatment of lesions that are involved both muscle and cartilage ”, explains Dr. Elena Rodríguez Iñigo, technical director of Amplicel. The Center clinic has a white cell culture room that follow good manufacturing standards that ensure the highest quality of production.

The use of myoblasts as therapeutic agents around the world is under investigation, and soon it is expected that it can be applied in clinical trials with patients suffering from various diseases affecting the musculoskeletal. Myopathies or muscular diseases can be caused by physiological defects or injuries. Fibrillar breaks are the most frequent and are among the best candidates to be treated with Myoblast cell therapy ”, says Dr. Rodríguez Iñigo. However, myoblasts research it goes much further and intends to also treat other pathologies where the muscles play a part such as urinary incontinence, muscular dystrophy or cardiomyopathies ”, adds.

sterile room of research and culture.

Cellular therapy is becoming a safe and effective alternative for the treatment of numerous diseases, explains Dr., due to lack of tissues and organs for transplantation ”. The decrease in the number of accidents of traffic and, as a result, the number of polytraumatized, as well as the longevity of the human being, has sent down the main sources of transplant, that are relied on tissue engineering ”, says.

Implantation of chondrocytes and myoblasts

The process of with Myoblast cell therapy could be similar to the one applied to treat the injury of cartilage with autologous chondrocytes. In the latter is made is: first we have to see through an arthroscopic surgery that the patient is susceptible to an implant. Where it does, a joint cartilage biopsy is done and is sent to crop to a white room ”, explains Dr. Pedro Guillén, head of the clinic of Traumatology Service Center. When you have the required number of cells proceeds to a second surgery is performed the implant. The patient will remain the two months without resting the tip, but walking with crutches, and then begin a process of rehabilitation and exercise for at least 8 or 9 months, after which you can start your usual activity.

The clinical center is the only Spanish Centre and the European second has its own Cleanroom in order to make the culture of chondrocytes. This allows ensure greater control the entire process of production and promotion of cells, as well as lower costs. Before had to make the crop abroad that worsened the conditions of the implant ”, indicates the doctor Guillén.